Senescent keratinocyte screening assays: AmorepacificRecent Research Landscape
Inconsistent biological aging markers in skin research lead to high failure rates in ingredient efficacy testing. These models standardize the induction of cellular senescence to enable reproducible screening of anti-inflammatory compounds.
What technical problems is Amorepacific addressing in Senescent keratinocyte screening assays?
Inaccurate physiological aging representation
(3)evidences
Conventional in vitro models fail to replicate the complex physiological state of aged human skin. Improving the fidelity of senescent models allows for more reliable screening of anti-aging compounds before clinical trials.
Keratinocyte senescence and inflammation
(2)evidences
Cellular aging and inflammatory responses in skin cells lead to tissue degradation and functional decline. Identifying materials that mitigate these specific failure modes allows for the prevention of age-related skin pathologies.