BASF

Last updated January 31, 2026

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F129l mutant cytochrome b strobilurins: BASFRecent Research Landscape

Standard strobilurin fungicides fail when pathogens develop the F129L mitochondrial mutation, leading to total crop loss. These compounds specifically target the altered binding pocket of the cytochrome b protein to restore fungicidal efficacy.

What technical problems is BASF addressing in F129l mutant cytochrome b strobilurins?

Fungicide resistance in phytopathogens

(28)evidences

Mutations like F129L in cytochrome b render existing strobilurin treatments ineffective. Overcoming this resistance ensures crop protection efficacy against evolving phytopathogenic strains.

Fungicide resistance mutation

(7)evidences

The F129L mutation in mitochondrial cytochrome b renders standard strobilurins ineffective. Overcoming this specific genetic resistance is necessary to maintain crop protection efficacy.