Hydantoinase catalyzed cyanohydrin esterification: BASFRecent Research Landscape
Inefficient racemic synthesis of glufosinate results in high waste and low herbicidal potency. This process utilizes biocatalytic conversion to ensure high-purity L-isomer yield and crystalline stability.
What technical problems is BASF addressing in Hydantoinase catalyzed cyanohydrin esterification?
Low enantiomeric product purity
(9)evidences
Suboptimal conversion rates and poor chiral purity during the transformation of cyanohydrin precursors. Improving these metrics ensures the economic viability and chemical efficacy of the final herbicide.
Low enantiomeric product purity
(6)evidences
Inefficient chiral separation and low optical purity in glufosinate synthesis. Achieving high enantiomeric excess ensures herbicidal potency and reduces chemical waste.
Low phosphorus cyanohydrin yield
(1)evidences
Inefficient conversion of cyanopropyl intermediates during the synthesis of phosphinic acid herbicides. Improving this step reduces byproduct formation and increases industrial throughput.