BASF

Last updated January 31, 2026

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Magnesium-regulated bacillus fermentation feed: BASFRecent Research Landscape

Protein degradation and metabolic stress in Bacillus hosts lead to low yields during fermentation. Precise salt concentration control stabilizes the host cell environment to maintain high-titer recombinant protein production.

What technical problems is BASF addressing in Magnesium-regulated bacillus fermentation feed?

Low heterologous protein expression yield

(16)evidences

Native regulatory proteins and promoters limit the metabolic flux and extracellular transport of target compounds. Overcoming these biological bottlenecks increases industrial production efficiency.

Microbial metabolite toxicity

(5)evidences

Firmicutes often exhibit poor DNA uptake and low conjugation rates during genetic modification. Overcoming this barrier allows for the rapid development of high-yield industrial strains.