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BASF

Last updated January 31, 2026
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Mesoionic imidazolium and pyrimidinium scaffolds: BASFRecent Research Landscape

Invertebrate pest resistance and off-target toxicity increase crop loss risks, which these specific fused bicyclic scaffolds mitigate through selective neurotoxic binding. Precise molecular substitution on the isoxazoline ring enhances potency to reduce required chemical application rates.

What technical problems is BASF addressing in Mesoionic imidazolium and pyrimidinium scaffolds?

Agricultural pest crop damage

(48)evidences

Existing chemical controls suffer from declining efficacy due to evolving biological resistance in agricultural and veterinary settings. Overcoming these defense mechanisms ensures continued protection of crops and livestock health.

Inadequate pest control efficacy

(11)evidences

Existing chemical treatments fail to eliminate resilient populations of bed bugs and rodents. Overcoming these biological defenses ensures effective eradication in domestic environments.

Invertebrate pest crop damage

(5)evidences

Destructive feeding and infestation by invertebrate pests lead to significant yield loss and degradation of plant propagation material. Mitigating this damage ensures agricultural productivity and seed viability.