Repeated use of single-mode herbicides leads to the survival of resistant weed populations. Combining multiple modes of action prevents the proliferation of resistant biotypes in tolerant crops.

Existing herbicidal compounds fail to eliminate a broad enough range of competitive plant species. Expanding the chemical classes to malonamides and phosphinates overcomes narrow efficacy ranges and prevents crop yield loss.

The survival of weed populations against standard chemical applications creates a loss of agricultural productivity. Mitigating this resistance ensures the continued efficacy of crop protection protocols.

Existing weed populations have developed biological defenses against single-mode chemical control. Combining specific inhibitors prevents the survival and spread of resistant biotypes.