Synthetic cis-regulatory nucleotide sequences: BASFRecent Research Landscape
Low protein yields in transgenic crops limit commercial viability due to weak endogenous transcription. These sequences engineer the transcriptional machinery to maximize target gene expression levels.
What technical problems is BASF addressing in Synthetic cis-regulatory nucleotide sequences?
Insufficient constitutive transgene expression
(23)evidences
Inability of modified plant cells to successfully transition into viable whole plants. Overcoming this bottleneck increases the throughput of genetic engineering and base editing applications.
Inadequate hybrid seed fertility
(9)evidences
Inconsistent restoration of male fertility in hybrid breeding systems. Stabilizing reproductive control ensures predictable seed production and crop yields.
Plasmodiophora brassicae infection susceptibility
(8)evidences
Fungal and protist infections cause significant biomass loss and seed quality degradation in oilseed crops. Mitigating these biological threats prevents catastrophic harvest failure and oil profile instability.