Bayer

Last updated January 31, 2026

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Acid-labile keto protective groups: BayerRecent Research Landscape

Uncontrolled substitution in polyfluorinated aromatics leads to low yields of high-value intermediates. These processes control site-specific functionalization to ensure high isomeric purity in specialty chemical precursors.

What technical problems is Bayer addressing in Acid-labile keto protective groups?

Intermediate instability during synthesis

(58)evidences

Inefficient conversion pathways and poor control over substitution patterns in halogenated aromatics and heterocycles. Improving these factors reduces waste and enables precise molecular architecture.

Low enantiomeric purity

(26)evidences

Inconsistent chiral yield and low optical purity in complex heterocyclic synthesis. Achieving high enantiomeric excess reduces byproduct waste and increases pharmacological potency.