Bayer

Last updated January 31, 2026

432

Innovation Areas

13,147

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104

Collaborations

Alpha-2c and task1/3 receptor dual-antagonism: BayerRecent Research Landscape

Upper airway collapse during sleep results from neurological signaling failures that increase patient mortality and healthcare costs. These innovations engineer specific synergistic chemical pairings to stabilize respiratory drive and muscle tone.

What technical problems is Bayer addressing in Alpha-2c and task1/3 receptor dual-antagonism?

Ischemic neuronal tissue damage

(21)evidences

Insufficient cyclic GMP signaling leads to stiffening of the cardiac muscle. Restoring this pathway addresses the mechanical failure of the heart to fill properly during diastole.

Upper airway collapse

(13)evidences

Loss of pharyngeal muscle tone during sleep leads to recurrent airway obstruction. Restoring neuromuscular stability prevents respiratory arrests and fragmented sleep architecture.