Gated voltammetric particle sensing: BayerRecent Research Landscape
Constitutive KRAS activation drives uncontrolled tumor proliferation and therapeutic resistance. These molecules disrupt the SOS1-KRAS exchange interface to arrest the oncogenic signaling cycle.
What technical problems is Bayer addressing in Gated voltammetric particle sensing?
Operating fluid particle contamination
(1)evidences
Uncontrolled signaling through the RAS-MAPK pathway drives oncogenesis and therapeutic resistance. Inhibiting SOS1 prevents the nucleotide exchange required for RAS to transition into its active state.
Inconsistent sample volume delivery
(1)evidences
Background noise and overlapping signals in liquid media prevent accurate quantification of target analytes. Reducing these spectral artifacts ensures higher sensitivity and measurement precision.