The cluster addresses the limitation of low natural yields of O-acetyl homoserine and L-methionine in microorganisms. Increasing precursor availability through foreign gene introduction overcomes metabolic bottlenecks to enable industrial-scale biosynthesis.

Standard amino acids often exhibit poor solubility and stability in aqueous or industrial formulations. Converting them to N-acetylated forms overcomes these physicochemical limitations for improved bioavailability and processing.