CJ CheilJedang

Last updated January 21, 2026

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Engineered decarboxylase metabolic pathways: CJ CheilJedangRecent Research Landscape

The technical lever is the modification of the ornithine decarboxylase (ODC) protein sequence to bypass metabolic feedback or increase catalytic flux. This enables high-titer microbial synthesis of putrescine as a bio-nylon precursor.

What technical problems is CJ CheilJedang addressing in Engineered decarboxylase metabolic pathways?

Low diamine biosynthetic yield

(3)evidences

The cluster focuses on overcoming low yields and slow kinetics in the metabolic production of cadaverine and putrescine. Improving these conversion rates enables cost-effective bio-based nylon precursor manufacturing.

Insufficient natural diamine biosynthesis

(2)evidences

Natural metabolic pathways often lack the efficiency to channel carbon precursors toward high-titer putrescine production. Overcoming this bottleneck enables industrial-scale bio-based chemical manufacturing.