CJ CheilJedang

Last updated January 21, 2026

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Homoserine acetyltransferase enzyme engineering: CJ CheilJedangRecent Research Landscape

The technical lever is the modification of the homoserine acetyltransferase polypeptide and its encoding polynucleotides. Engineering this specific enzymatic activity controls the metabolic flux toward O-acetyl homoserine, a critical precursor for high-yield L-methionine biosynthesis.

What technical problems is CJ CheilJedang addressing in Homoserine acetyltransferase enzyme engineering?

Low metabolic precursor flux

(18)evidences

The cluster addresses the limited natural production rates of O-acetyl homoserine which restricts downstream L-methionine yields. Enhancing this flux is critical for industrial-scale amino acid fermentation efficiency.