Colgate

Last updated January 31, 2026

Innovation Areas

915

Inventors

Collaborations

Sorbitan polyoxyethylene ester surfactant system: ColgateRecent Research Landscape

Poor mucosal adhesion and rapid wash-out of active ingredients reduce the efficacy of oral rinses. Controlling the concentration and chain length of hyaluronic acid ensures optimal bioadhesion and tissue hydration.

What technical problems is Colgate addressing in Sorbitan polyoxyethylene ester surfactant system?

Oral tissue irritation

(5)evidences

Lipophilic antimicrobial or flavoring agents often fail to remain stable in aqueous oral care bases. Improving solubility prevents phase separation and ensures consistent delivery of therapeutic components.

Acute dental nerve hypersensitivity

(3)evidences

Insufficient moisture retention on oral surfaces leads to tissue irritation and discomfort. Improving hydration longevity enhances therapeutic efficacy and patient comfort.

Microbial contamination and bioburden

(1)evidences

Susceptibility to bacterial and fungal growth in aqueous surfactant systems. Preventing contamination ensures product safety and shelf-life stability.