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Last updated January 31, 2026
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Zinc arginine serine synergistic complex: ColgateRecent Research Landscape

Zinc salts often cause astringency and instability in oral formulations, which is mitigated by engineering an alginate-calcium structural network to control ion release. This stabilization prevents ingredient degradation and improves the sensory profile of the dentifrice.

What technical problems is Colgate addressing in Zinc arginine serine synergistic complex?

Oral biofilm accumulation

(6)evidences

Uncontrolled microbial growth and plaque formation lead to tooth decay and periodontal disease. Inhibiting this accumulation prevents oral health deterioration.

Inadequate oral mucosal immunity

(4)evidences

Insufficient natural production of secretory IgA and mucins leads to weakened biological defenses in the oral cavity. Enhancing these protective barriers prevents pathogen colonization and maintains tissue integrity.