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DSM-Firmenich

Last updated February 26, 2026
33
Innovation Areas
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Selective bitter receptor antagonism: DSM-FirmenichLast 5 Years Research Landscape

Off-notes in pharmaceutical and functional food formulations trigger sensory rejection and reduce consumer compliance. This technology identifies and deploys specific molecular antagonists to stabilize the sensory profile by blocking signal transduction at the receptor level.

What technical problems is DSM-Firmenich addressing in Selective bitter receptor antagonism?

Unpleasant citrus bitterness perception

(6)evidences

Natural citrus extracts and active pharmaceutical ingredients often trigger aversive gustatory responses. Eliminating these off-notes is critical for consumer acceptance and oral delivery efficacy.

Unpleasant gustatory bitterness perception

(4)evidences

Natural and synthetic ingredients often trigger off-putting bitter taste receptors in food and pharmaceutical applications. Eliminating this sensory defect improves consumer acceptance and palatability of functional formulations.