Beta Lactoglobulin Environmental Fate & Ecotoxicity

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Functions

HAIR ConditioningSKIN Conditioning

What are the physicochemical properties of Beta lactoglobulin?

PropertyValueCategory
residues162 residuesAnalytical Properties
oligomeric statepredominantly dimeric in physiological conditions; dissociates to monomer below pH 3; also occurs as tetrameric, octameric and other multimeric formsAnalytical Properties
amino acid residues162 amino acid residues, 162Analytical Properties
structure classificationlipocalin familyAnalytical Properties
binding pocket ligandscholesterol and vitamin D2 bound to central binding cavity at pH 7.3 (structures reported at resolutions 2.0 Å and 2.4 Å respectively; R = 0.221; Rfree = 0.295 for cholesterol; R = 0.212; Rfree = 0.297 for vitamin D2; not all ligand densities fully visible)Analytical Properties
structureglobular protein of the lipocalin family; eight-stranded antiparallel β-barrel with a calyx; contains seven major strands of beta pleated sheet; small section of alpha helixAnalytical Properties
disulfide bondstwo internal disulfide bridges; a single sulfhydryl group at Cys121Analytical Properties
free sulfhydryl groupCys121 buried in the protein; exposed under heating or disruption leads to disulfide exchangeAnalytical Properties
oligomeric state at neutral pHnon-covalently linked dimer (at neutral pH)Analytical Properties
Assay≥85% (PAGE)Analytical Properties