Chemical degradation of bioactive peptides in acidic environments leads to formulation instability and loss of efficacy. This lever utilizes polyol-based stabilization to maintain the structural integrity of polyhydroxyacids and beta-hydroxyacids within a single delivery system.
Poor solubility and stability of botanical compounds like menthol often lead to insufficient skin penetration and moisture retention. Ensuring effective transport of these actives through complex polymer matrices prevents loss of therapeutic efficacy.