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Loreal

Last updated January 31, 2026
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Indole derivative keratin modulators: LorealRecent Research Landscape

Oxidative and structural degradation of hair and skin proteins leads to visible aging and damage. These formulations utilize specific indole-based metabolic precursors to chemically reinforce keratin integrity.

What technical problems is Loreal addressing in Indole derivative keratin modulators?

Accelerated dermal tissue degradation

(21)evidences

Environmental and chemical stressors cause irreversible damage to the integrity of hair and skin proteins. Preventing or reversing this deterioration maintains the physical properties and aesthetic quality of keratin materials.

Skin microbiome dysbiosis

(19)evidences

Imbalance of bacterial skin flora leads to compromised barrier function and dermatological conditions. Restoring microbial equilibrium prevents opportunistic pathogen colonization and inflammatory responses.

Impaired epidermal barrier function

(4)evidences

Unwanted melanin accumulation and hyperpigmentation disorders. Reducing these effects restores aesthetic uniformity and skin health.