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Loreal

Last updated January 31, 2026
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Thiopyridinone chelating agent stabilization: LorealRecent Research Landscape

Oxidative degradation of thiopyridinone compounds reduces the efficacy of keratin depigmentation treatments. This lever stabilizes the active species through precise coordination with chelating agents to maintain formulation potency.

What technical problems is Loreal addressing in Thiopyridinone chelating agent stabilization?

Oxidative chemical degradation

(30)evidences

Thiopyridinone compounds are chemically unstable and prone to rapid decomposition when exposed to environmental factors. Preventing this breakdown maintains the active concentration and functional efficacy of the chemical formulation.

Excessive skin melanin accumulation

(5)evidences

Excessive melanin accumulation leads to visible age spots and uneven skin tone. Reducing this localized pigmentation improves aesthetic appearance and skin uniformity.

Keratinous pigment accumulation

(4)evidences

Natural melanin and exogenous pigments cause unwanted dark tones in hair and skin. Eliminating these pigments provides the aesthetic advantage of uniform lightening and brightening.