Membrane flow distribution geometry: MerckRecent Research Landscape
Non-uniform fluid distribution in membrane chromatography causes premature breakthrough and reduced binding capacity. These innovations engineer flow path geometries to eliminate dead zones and ensure even solute loading across the membrane surface.
What technical problems is Merck addressing in Membrane flow distribution geometry?
Inadequate molecular binding selectivity
(7)evidences
Structural collapse during drying and non-uniform particle retention across filter depth. Eliminating these defects ensures predictable separation efficiency and prevents premature media clogging.
Nonuniform fluid residence time
(4)evidences
Inconsistent flow patterns and void spaces lead to inefficient mass transfer and cellular hypoxia. Eliminating these dead zones ensures uniform nutrient delivery and prevents localized degradation.