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Last updated January 31, 2026
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Optical raman probe interfaces: MerckRecent Research Landscape

Signal interference from stray light and interface mismatches degrades real-time sensing accuracy in single-use bioprocessing. These innovations engineer the physical probe-to-vessel coupling to isolate optical paths and ensure high-fidelity data.

What technical problems is Merck addressing in Optical raman probe interfaces?

Sample contamination and degradation

(15)evidences

Current portable systems lack integrated mixing and filtration capabilities for rapid purification in remote environments. Solving this ensures safe potable water access during mobile or drone-assisted operations.

Inaccessible real-time biochemical monitoring

(12)evidences

Environmental and process-induced noise in bioreactors degrades the accuracy of optical sensor readings. Mitigating these disturbances ensures reliable real-time monitoring of critical process parameters.

Incomplete analyte phase capture

(10)evidences

Loss of volatile or particulate components during collection leads to inaccurate chemical analysis. Ensuring simultaneous capture of both aerosol and vapor phases prevents underreporting of total analyte concentration.