Biological catalysts and DNA polymerases often denature or lose activity at elevated temperatures required for industrial processing or PCR. Overcoming this thermal degradation allows for consistent molecular amplification and efficient biosynthesis under high-heat conditions.

Microbial degradation and biochemical synthesis are severely inhibited or halted in polar and sub-zero environments. Overcoming this thermal limitation allows for environmental remediation and industrial processing in extreme climates.

Biocatalytic processes often stall or fail in cold environments due to high activation energy requirements. Overcoming this thermal limitation allows for industrial waste processing and bioremediation in non-temperate climates.

Agricultural yields are severely limited by uncontrolled bacterial and fungal infections such as canker and wilt. Mitigating these biological threats prevents total crop failure and stabilizes food production systems.