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Nestle

Last updated January 31, 2026
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Human milk oligosaccharide bioactives: NestleRecent Research Landscape

Nutritional variability in synthetic milk substitutes leads to suboptimal neonatal development and metabolic risks. Precise titration of lipid-protein fractions mimics human milk composition to ensure physiological compatibility.

What technical problems is Nestle addressing in Human milk oligosaccharide bioactives?

Inaccurate infant physiological assessment

(6)evidences

Severe allergic reactions and gastrointestinal distress caused by intact bovine proteins in standard formulas. Eliminating these triggers prevents systemic inflammation and malabsorption in sensitive neonates.

Infant immune system hypersensitivity

(5)evidences

Insufficient microbial diversity and low short-chain fatty acid production in the developing infant intestine. Addressing this prevents pathogenic susceptibility and developmental delays.

Infant immune system vulnerability

(4)evidences

Infants face severe risks from necrotizing enterocolitis and post-surgical inflammation. Preventing tissue degradation and failure ensures survival and proper nutrient absorption.

Infant intestinal microbiota dysbiosis

(3)evidences

Imbalanced gut flora leads to non-rotavirus diarrhea and insufficient short-chain fatty acid production. Restoring microbial equilibrium prevents gastrointestinal infections and metabolic deficiencies in infants.