Nicotine and tobacco extracts trigger trigeminal nerve receptors, causing burning sensations that limit consumer acceptance of high-strength oral products.
Lipophilic flavor cores frequently migrate through hydrocolloid shells or degrade when exposed to moisture during storage and heating.
Unprotected contact between raw tobacco extracts and oral tissues causes immediate localized stinging and poor organoleptic stability.
Nicotine molecules trigger specific ion channels and sensory receptors that produce involuntary burning sensations and throat harshness.