Procter & Gamble

Last updated January 21, 2026

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Retinoid photostability and bilirubin degradation: Procter & GambleRecent Research Landscape

Engineering the chemical stability of retinoids and the enzymatic or oxidative degradation of bilirubin. This enables effective topical treatments for skin discoloration and aging without ingredient degradation.

What technical problems is Procter & Gamble addressing in Retinoid photostability and bilirubin degradation?

Visible signs of cutaneous aging

(12)evidences

The keywords focus on improving skin appearance and testing samples to address structural or aesthetic decline. Mitigating these signs provides a competitive advantage in dermatological efficacy and consumer satisfaction.

Excessive cutaneous bilirubin accumulation

(10)evidences

The accumulation of bilirubin in skin tissues leads to visible discoloration and potential cellular toxicity. Addressing this degradation bottleneck improves skin clarity and metabolic health.

Retinoid oxidative degradation

(8)evidences

Retinoids are highly sensitive to light and air, leading to rapid loss of biological activity. Preventing this chemical breakdown ensures the product remains effective throughout its shelf life.