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Procter & Gamble

Last updated January 21, 2026
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Semisolid active dispersion matrices: Procter & GambleRecent Research Landscape

Engineering the rheological phase and adhesive properties of a semisolid carrier to control the release kinetics of active agents on oral surfaces. This enables prolonged contact time and targeted delivery for localized treatments like whitening.

What technical problems is Procter & Gamble addressing in Semisolid active dispersion matrices?

Unstable active agent delivery

(29)evidences

Semisolid oral dispersions and peroxide-based compositions often suffer from premature degradation or poor retention of active ingredients during application. Stabilizing these agents ensures consistent therapeutic efficacy and prolonged contact time on oral surfaces.

Dentin hypersensitivity and enamel erosion

(11)evidences

The use of oxalic and dicarboxylic acids in oral compositions is primarily aimed at occluding dentinal tubules to prevent nerve stimulation. Addressing this failure of the tooth's protective barrier provides a technical advantage in pain reduction and enamel protection.

Undetected dental biofilm accumulation

(4)evidences

The cluster focuses on the persistent accumulation of organic stains on dental enamel that require chemical or light-activated intervention. Addressing this improves aesthetic outcomes and patient compliance in oral hygiene regimens.