Engineering the rheological phase and adhesive properties of a semisolid carrier to control the release kinetics of active agents on oral surfaces. This enables prolonged contact time and targeted delivery for localized treatments like whitening.
Semisolid oral dispersions and peroxide-based compositions often suffer from premature degradation or poor retention of active ingredients during application. Stabilizing these agents ensures consistent therapeutic efficacy and prolonged contact time on oral surfaces.
The use of oxalic and dicarboxylic acids in oral compositions is primarily aimed at occluding dentinal tubules to prevent nerve stimulation. Addressing this failure of the tooth's protective barrier provides a technical advantage in pain reduction and enamel protection.