# Protein design and engineering using AI

Topic radar · 1,158 documents · 2021-01-01–2026-07-30 · updated 2026-08-07

Canonical: https://slate.greyb.com/radar/protein-design-and-engineering-using-ai/innovations

## Overview


Structural instability in novel protein architectures resolved through deep generative modeling of de novo sequences



Binding affinity limitations in therapeutic antibodies overcome via CDR library design and variable region modeling



Functional sequence scarcity for specialized protein applications addressed through machine learning models and library design


## Areas

- Generative Foundations & Platforms · 393 documents
- Therapeutics & Immunology · 321 documents
- Biocatalysis & Industrial Enzymes · 270 documents
- Synthetic Biology & Gene Editing · 142 documents
- Antimicrobials & AgTech · 59 documents