Microneedle projection array geometry: ShiseidoRecent Research Landscape
Inconsistent skin penetration and needle breakage lead to unreliable drug delivery and patient safety risks. Engineering the specific needle architecture and mechanical properties ensures predictable transdermal flux and structural integrity.
What technical problems is Shiseido addressing in Microneedle projection array geometry?
Insufficient skin penetration depth
(1)evidences
The stratum corneum acts as a physical barrier that prevents effective transdermal delivery. Overcoming this resistance ensures consistent drug flux and therapeutic efficacy.