Microbial skin therapeutics: Skin MicrobiomeLast 5 Years Research Landscape
Pathogenic dysbiosis and biofilm formation drive chronic inflammatory skin conditions, requiring targeted commensal strains or metabolites to restore epidermal barrier function.
What technical problems is Skin Microbiome addressing in Microbial skin therapeutics?
Pathogenic biofilm formation
(75)evidences
Staphylococcus aureus and Pseudomonas aeruginosa colonize skin surfaces through protective extracellular matrices that resist standard antimicrobial treatments.
Epidermal barrier enzymatic dysfunction
(60)evidences
Imbalanced microbial metabolite levels disrupt skin permeability and protease activity, leading to chronic inflammatory conditions like atopic dermatitis.