Skin irritation and delayed efficacy of traditional retinoids drive consumer churn, which is mitigated by integrating instant-acting optical brighteners with non-irritating bio-retinol alternatives. This dual-action approach provides immediate visual correction while maintaining long-term therapeutic benefits without the typical side effects of pure retinol.
Retinoids cause significant irritation and PTGS2-mediated inflammatory responses during dermatological treatment. Addressing this limitation allows for effective skin therapy without the adverse side effects that typically lead to patient non-compliance.