Syngenta

Last updated January 31, 2026

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Cyclopropyl and azole amide scaffolds: SyngentaRecent Research Landscape

Crop loss from pest resistance and environmental degradation increases operational risk, which is mitigated through the synthesis of specific heterocyclic amide structures to ensure targeted neurotoxic or metabolic disruption in parasites. These proprietary molecular frameworks provide the necessary chemical stability and binding affinity to protect propagation materials where generic pesticides fail.

What technical problems is Syngenta addressing in Cyclopropyl and azole amide scaffolds?

Diamide insecticide resistance

(7)evidences

Existing pest populations have developed biological defenses against standard diamide chemistries. Overcoming this resistance restores chemical control efficacy over destructive agricultural species.

Inadequate crop pest control

(5)evidences

Existing chemical agents suffer from insufficient lethality or narrow spectrums against agricultural pests. Improving control efficacy prevents crop yield loss and overcomes pest resistance.

Inadequate crop pest control

(4)evidences

Existing chemical scaffolds fail to provide adequate mortality rates or residual activity against resistant pest populations. Improving potency and spectrum of action prevents crop loss and reduces application frequency.

Invertebrate pest crop damage

(3)evidences

Insects, mites, and nematodes cause significant yield loss and degradation of plant propagation material. Mitigating these biological threats ensures the survival and productivity of agricultural assets.