Uncontrolled proliferation of harmful microorganisms in agricultural or industrial settings. Mitigating this risk prevents crop loss and material degradation.

Low molecular interaction strength between heterocyclic scaffolds and target enzymes leads to poor therapeutic potency. Enhancing binding affinity ensures effective inhibition of pathological signaling pathways.

Uncontrolled fungal and bacterial growth on crops leads to significant yield loss and food spoilage. Preventing these infestations ensures agricultural productivity and plant health.