Polymorphic and cocrystal phase engineering: SyngentaRecent Research Landscape
Unstable active ingredient phases lead to inconsistent bioavailability and shelf-life degradation. Precise control of the monohydrate crystalline lattice ensures thermodynamic stability and predictable dissolution rates.
What technical problems is Syngenta addressing in Polymorphic and cocrystal phase engineering?
Poor aqueous solubility
(5)evidences
Unpredictable phase transitions and hydration states lead to inconsistent bioavailability and shelf-life. Controlling polymorphism prevents unintended structural degradation in complex formulations.