Syngenta

Last updated January 31, 2026

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Pyrazole alkylation and amidation chemistry: SyngentaRecent Research Landscape

Inefficient chiral separation and low regioselectivity in heterocyclic synthesis drive up active ingredient costs. These innovations utilize enantioselective catalytic pathways to ensure high-purity isomer production.

What technical problems is Syngenta addressing in Pyrazole alkylation and amidation chemistry?

Regioselectivity control failure

(6)evidences

Uncontrolled isomer formation during alkylation and amidation leads to poor yields of the desired regioisomer. Achieving high isomeric purity reduces costly separation steps and material waste in large-scale synthesis.