Syngenta

Last updated January 31, 2026

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Pyridine and trifluoroethanone synthetic pathways: SyngentaRecent Research Landscape

Inefficient substitution patterns in aromatic precursors lead to low yields and costly purification steps. These processes utilize specific catalytic pathways to control regioselectivity and functional group placement in complex intermediates.

What technical problems is Syngenta addressing in Pyridine and trifluoroethanone synthetic pathways?

Low stereochemical purity

(13)evidences

Inconsistent control over enantiomeric and diastereomeric ratios during sulfur and amine synthesis. Achieving high isomeric enrichment ensures predictable biological activity and reduces off-target effects.

Low enantiomeric purity

(11)evidences

Uncontrolled substitution patterns during the synthesis of complex heteroarenes lead to poor isomeric purity. Achieving precise positional control enables the production of high-value pharmaceutical intermediates with fewer purification steps.

Low herbicidal synthesis yields

(8)evidences

Suboptimal conversion rates and poor regioselectivity in multi-step heterocyclic synthesis. Improving yield reduces waste and lowers production costs for complex agrochemical intermediates.