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Tate & Lyle

Last updated January 21, 2026
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Glycosyltransferase mediated steviol glycosylation: Tate & LyleRecent Research Landscape

The cluster focuses on the engineering of specific GT and SUS enzymes to control the regioselective glycosylation of steviol glycosides. This enables the precise molecular transformation of common stevia compounds into high-value, rare rebaudiosides.

What technical problems is Tate & Lyle addressing in Glycosyltransferase mediated steviol glycosylation?

Bitter aftertaste and lingering sweetness

(8)evidences

Natural high-intensity sweeteners often suffer from lingering bitterness, metallic aftertastes, or poor mouthfeel compared to sucrose. Modifying glycosylation patterns aims to eliminate these specific sensory defects to achieve a sugar-like taste profile.

Excessive dietary glycemic response

(5)evidences

The keywords focus on flavor-altering and sweetness-enhancing compositions for low-sugar products. Addressing off-notes and lingering bitterness in high-potency sweeteners is critical for consumer acceptance and sensory parity with sucrose.

Low enzymatic conversion efficiency

(5)evidences

Natural glycosyltransferases often exhibit poor catalytic rates and substrate specificity for steviol glycosides. Overcoming these kinetic bottlenecks enables the industrial-scale production of high-intensity sweeteners.