Merck

Last updated January 31, 2026

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Atm kinase signaling inhibitors: MerckRecent Research Landscape

Viral replication cycles lead to rapid infection spread and high healthcare costs, which are mitigated through the engineering of specific benzamide-based protease inhibitors. These chemical structures provide a targeted mechanism to block viral maturation across multiple coronavirus strains.

What technical problems is Merck addressing in Atm kinase signaling inhibitors?

Broad spectrum viral resistance

(6)evidences

Viral proliferation and the resulting cellular damage represent the primary failure state. Inhibiting these processes prevents systemic infection and severe disease progression.

Viral replication and pathogenesis

(5)evidences

Uncontrolled viral proliferation leads to severe respiratory distress and host cell damage. Inhibiting these processes prevents systemic infection and reduces morbidity in vulnerable populations.