L Leucine
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Identifiers
FormulaC6H13NO2·CAS61-90-5·EC200-522-0
Functions
AntistaticHAIR Conditioning +1 more
What does L leucine do?
An essential amino acid; [Merck Index] Used as a flavoring agent and nutritional supplement for foods; Used in biochemical research
How is L leucine used clinically?
Indicated to assist in the prevention of the breakdown of muscle proteins that sometimes occur after trauma or severe stress
What are the physicochemical properties of L leucine?
| Property | Value | Category |
|---|---|---|
| Physical Description | Dry Powder, White solid; [Merck Index] White powder; [Sigma-Aldrich MSDS], Solid, Small white lustrous plates or crystalline powder; odourless | Appearance |
| Color/Form | White glistening hexagonal plates from aqueous alcohol, White crystals | Appearance |
| Solubility | 21500 mg/L (at 25 °C), Leaflets from water. Sweet taste. Decomposes at 232 °C (also reported as 290 °C). Sublimes. pK1 = 2.36; pK2 = 9.60. Solubility in water (g/L): 7.97 (0 °C); 9.91 (25 °C); 14.06 (50 °C); 22.76 (75 °C); 42.06 (100 °C); in 90% alcohol: 1.3. Insoluble in ether. /Leucine DL-form/, Solubility in 99% alcohol: 0.72; in acetic acid: 10.9. Insoluble in ether, Solubility in water (g/L): 22.7 (0 °C); 24.26 (25 °C); 28.87 (50 °C); 38.23 (75 °C); 56.38 (100 °C), In water, 2.15X10+4 mg/L at 25 °C, 21.5 mg/mL, Soluble in water, acetic acid, dilute HCl, and alkaline hydroxides and carbonates, Slightly soluble (in ethanol) | Formulation Relevant Properties |
| LogP | -1.52, log Kow = -1.52 | Formulation Relevant Properties |
| Acidic pKa | 2.38 | Formulation Relevant Properties |
| Basic pKa | 9.61 | Formulation Relevant Properties |
| pKa | 2.35 (at 13 °C) | Formulation Relevant Properties |
| Dissociation Constants | pKa = 2.35 | Formulation Relevant Properties |
| Boiling Point | Sublimes at 145-148 °C. Decomposes at 293-295 °C (rapid heating, sealed tube) | Handling Relevant Properties |
| Melting Point | 293 °C, 268 - 288 °C | Handling Relevant Properties |